
Prostep nicotine patch. How to use Prostep Patch, Transdermal 24 Hours. If necessary, clip hair from the site before applying the patch. Do not shave the area. Remove the patch from the package, peel off the protective strip, and immediately apply the patch to the skin. Press firmly for 10 to 20 seconds to make sure the patch stays in place. ProStep (Nicotine Transdermal System) Patches Company: Elan Pharmaceutical Research Corp. Application No.: 19-983/S-012 Approval Date:. Approval Letter(s) (PDF) (989 KB) Medical Review(s) (PDF) (2.4 MB) Clinical Pharmacology Biopharmaceutics Review(s) (PDF) (2.2 MB) Administrative Document(s) Part 1 (PDF) (3 MB).